Titanium Reactor Selection Guide| All-titanium vs composite plate vs lining +5 steps to avoid pits

Published by Engineering Team, Shaanxi Qianyi Tuoda Technology Co., Ltd on 2026-07-24

Equipment supervisor of a pharmaceutical intermediate enterprise in Shandong encountered equipment corrosion problems, Chlorination reaction of original 316L stainless steel reactor containing 3000ppm chloride ion, Pitting and perforation only 3 months old, Material contamination results in intermediate scrap.After replacing TA2 titanium reactor, the equipment has been running stably for 5 years, and the corrosion situation has been obviously improved.Under chlorine-containing oxidizing medium condition, 316L is prone to pitting, Titanium is resistant to chloride ion corrosion, Material cleanliness, COMPREHENSIVE CHARACTERISTICS OF PRESSURE RESISTANCE, Widely used in chemical industry, medicine, New energy materials.Titanium Reactor IntegrationTitanium Plate、Titanium flangeheat exchange component, stirring member, 0.5‑5m³ All titanium structure is often used for small and medium-sized equipment, Titanium steel clad plate shall be selected for medium and low pressure working conditions with volume greater than 5m³, 30 - 50% cost reduction can be achieved.

Titanium reactor is divided into three types of structure: titanium, titanium steel clad plate and titanium lining.Full titanium kettle cylinder, head plate, TA2 titanium is used for connecting pipes, medium clean, No carbon steel precipitation contamination, Adapt to small volumes, high pressure working, However, the overall investment is high, Suitable for equipment with wall thickness ≤13mm, High purity processes and high pressure hydrogenation scenarios.Titanium steel clad plate reaction kettle with Q345R carbon steel as base bearing pressure, 2‑4mm TA2 coating for corrosion protection, High-volume project cost advantage outstanding, Ability to reduce input by 30‑50%need to pay attention to, If the titanium coating is perforated, Bulging damage will occur when medium penetrates into carbon steel interface, Mostly used for atmospheric pressure with wall thickness greater than 20mm, Medium and low pressure large volume working condition, The cladding thickness shall not be less than 2mm, Avoiding the risk of weld breakdown, The shear strength of composite interface shall not be lower than 140MPa according to NB/T 47002 standard.Titanium lined kettle adopts carbon steel shell inner liningTitanium PlateThe cost is low, the structure is only suitable for atmospheric pressure large tank, not suitable for pressure production.

Function of common jacket, coil, electric heating, high pressure hydrogenation, magnetic drive five kettle type.Jacket kettle rely on jacket into steam or heat transfer oil to complete heat exchange, belonging to the general heating and cooling structure;The inner coil kettle relies on the heat exchange of the inner coil of the kettle to adapt to the reaction requiring a large heat transfer area;Electric heating kettle configuration electric jacket, mostly used in pharmaceutical industry small test, pilot test;The high pressure hydrogenation kettle is suitable for high temperature and high pressure catalytic hydrogenation process, and is equipped with magnetic stirring;Magnetic drive kettle adopts magnetic stirring structure to eliminate shaft seal leakage risk and meet high clean production.Stirring forms include easy to maintain top-down, Side entry type suitable for shallow liquid condition of large tank, and a magnetic drive structure featuring no leakage.

Different industrial media are adapted to different titanium reaction kettle structures, and the chlor-alkali wet chlorine salt water working condition is preferably full titanium;PTA bromine-containing acetic acid, hydrometallurgical leaching, seawater desalination, electroplating scenarios are mostly composite plates;aseptic synthesis of pharmaceutical GMP, New Energy Electrolyte, Oxidation of high salinity wastewater, Strict control of metal ions, All titanium kettle recommended.It should be noted that titanium reactors are not suitable for hydrofluoric acid, nor for concentrated hydrochloric acid boiling conditions for a long time.Compared to other corrosion resistant equipment, Hastelloy is corrosion resistant but has high procurement costs, Glass-lining is susceptible to thermal shock damage, Temperature resistance of fluorine-lined materials, Limited wear resistance, Titanium material has self-healing ability in passivation film containing oxychloride environment, It is an important choice for chlorine-containing conditions.

In terms of material configuration, TA2 shall be selected for cylinder, head and connecting pipe under normal working condition;Strong reducing acid crevice corrosion risk scenario upgrade TA10;TA9 can be selected for local nozzle sealing nipple.stirring shaft, blade, Conventional TA2, TA10 is selected as strong reducing acid, TC4 is used for high-pressure stress partsFasteners are also matched with TA2, TA10 and TC4 according to working conditions;Mechanical seals generally use silicon carbide and tungsten carbide grinding pairs with titanium alloy bushings.

price subject volume, structural configuration effect, PN1.6 Configuration Stirring and Double Face Mechanical Seal, 0.5m³ TA2 titanium kettle reference price 3.5‑ 50,000 yuan, 1m³ Full titanium 5‑ 70,000 yuan, 2m³7‑ 100,000 yuan, 5m³ Full titanium 12‑ 180,000 yuan.The same configuration 1m³ TA2 + Q345R composite plate kettle reference 35,000 yuan, about 55‑70% of all titanium equipment.Equipment cost consists of titanium body, clad rolling cost, machining hole, weld flaw detection, stirring transmission, Inspection annealing is composed of multiple parts.

Model selection needs to confirm the nominal volume, design pressure, design temperature, aspect ratio, inner wall finish five parameters.The volume shall reserve a filling factor of 10‑20% on the basis of batch materials;The pressure covers the normal pressure to 35MPa, and the hydrogenation working pressure can reach more than 10MPa.Temperature routine ‑20~300℃;The length-diameter ratio of vertical kettle is generally 1‑1.3;General working conditions inner wall Ra≤0.8μm, pharmaceutical GMP requirements Ra≤0.4μm.

Avoid multiple risks during processing, Titanium material will absorb hydrogen and oxygen at temperature over 400℃, Welding seam welding must be double-sided high purity argon protectionIt is difficult to correct the deformation of titanium after welding, and anti-deformation tooling is needed.Titanium and carbon steel can not be directly welded, using composite plates or loose flange transition;Vacuum stress relief annealing at 550‑600℃ is required after welding, and air furnace cannot be used;Pharmaceutical grade polishing requires a progressive treatment with diamond abrasive paste.Purchase verification needs to check furnace lot warranty, spectrum detect iron and oxygen element, Thickness measurement and random inspection of wall thickness, Confirm the qualification related to pressure vessel manufacturing.

Baoji China Titanium Valley gathers a large number of titanium processing enterprises, Shaanxi Qianyi Tuoda Technology can provide all titanium, titanium steel clad plate, Titanium lining a variety of titanium reactor customization, support jacket, coiler, magnetic drive, Hydrogenation kettle and other functional forms, Compliance with GB/T150, NB/T47002 for pressure vessel design and manufacture, Pharmaceutical grade electropolishing available, vacuum postweld annealing, Full set of inspection report, Engineers can combine volumes, pressure, Medium selection reference is given.

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frequently asked questions

Q: How to choose titanium and titanium steel clad plate? A: wall thickness ≤13mm, high purity process, high pressure hydrogenation priority all titanium;Composite solutions can be evaluated if the wall thickness is greater than 13mm;Preferred composite plate with wall thickness greater than 20mm, The thickness of the cladding shall not be less than 2mm, Interface shear strength ≥140MPa.

Q: Can titanium reactors be used for hydrofluoric acid? Answer: Not applicable, hydrofluoric acid will destroy titanium passivation film, fluorine conditions recommended to use Hastelloy or PTFE lined equipment.

Q: Can pharmaceutical GMP use titanium reactors? a, may, All titanium structure selected, Electropolishing inner wall to Ra≤0.4μm, Priority magnetic drive to eliminate shaft seal leakage hidden danger.

disclaimer

This article selection ideas, Price range is based on industry project experience, For technical reference only, Not as engineering design, Direct basis for purchasing contract.Pressure vessel equipment selection, design, manufacture, Be sure to have qualified engineers and technicians combined with site conditions, Current GB/T150, JB/T4745 Assessment.